In vitro activities of the new antitubercular agents PA-824 and BTZ043 against Nocardia brasiliensis.

نویسندگان

  • Lucio Vera-Cabrera
  • Mayra Paola Campos-Rivera
  • Norma Alejandra Gonzalez-Martinez
  • Jorge Ocampo-Candiani
  • Stewart T Cole
چکیده

The in vitro activity of PA-824 and BTZ043 against 30 Nocardia brasiliensis isolates was tested. The MIC(50) and MIC(90) values for PA-824 were both >64 μg/ml. The same values for BTZ043 were 0.125 and 0.250 μg/ml. Given the MIC values for benzothiazinone (BTZ) compounds, we consider them good candidates to be tested in vivo against N. brasiliensis.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 7  شماره 

صفحات  -

تاریخ انتشار 2012